KEGG2Net: Deducing gene interaction networks and acyclic graphs from KEGG pathways
نویسندگان
چکیده
منابع مشابه
Prediction of Effective Drug Combinations by Chemical Interaction, Protein Interaction and Target Enrichment of KEGG Pathways
Drug combinatorial therapy could be more effective in treating some complex diseases than single agents due to better efficacy and reduced side effects. Although some drug combinations are being used, their underlying molecular mechanisms are still poorly understood. Therefore, it is of great interest to deduce a novel drug combination by their molecular mechanisms in a robust and rigorous way....
متن کامل[Relativity of gene expression and co-regulated gene patterns in feature KEGG pathways].
We revealed the feature pathways by computing the classification error rates of out-of-bag (OOB) by random forests combined with pathway analysis. At each feature pathway, the relativity of gene expression was studied and the co-regulated gene patterns under different experiment conditions were analyzed by MAP (Mining attribute profile) algorithm. The discovered patterns were also clustered by ...
متن کاملEffector-triggered immunity signaling: from gene-for-gene pathways to protein-protein interaction networks.
In its simplicity and testability, Flor's gene-for-gene hypothesis has been a powerful driver in plant immunity research for decades. Once the molecular underpinnings of gene-for-gene resistance had come into sharper focus, there was a reassessment of Flor's hypothesis and a name change to effector-triggered immunity. As implied by the name change and exemplified by pioneering studies, plant im...
متن کاملDeducing Intracellular Disb1buUons of Metabolic Pathways from Genomic Data
In the recent ycars, a large number of genomes from a variety of different organisms have been sequenced. Most of the sequence data has been publicly released and can be assessed by interested users. However, this wca.lth ofinformation is currendyundercxploitcd by scientists not directly invoh•ed in genome anno1ation. This is partially because sequencing, assembly, and aummatcd at>no~tion can b...
متن کاملBioJS component to visualize KEGG Pathways
Signaling pathways provide essential information on complex Summary: regulatory processes within the cell. They are moreover widely used to interpret and integrate data from large-scale studies, such as expression or functional screens. We present KEGGViewer a BioJS component to visualize KEGG pathways and to allow their visual integration with functional data. KEGGViewer is an open-source tool...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: EMBnet.journal
سال: 2021
ISSN: 2226-6089
DOI: 10.14806/ej.26.0.949